Rafael Nadal, Novak Djokovic, and Carlos Alcaraz have all faced surprising second-round defeats in Grand Slam tournaments during their peak years (Source: Getty).
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#6 Roger Federer vs Andreas Seppi – Australian Open 2015
#5 Novak Djokovic vs Denis Istomin – Australian Open 2017
#4 Roger Federer vs Sergiy Stakhovsky – Wimbledon 2013
#3 Rafael Nadal vs Steve Darcis – Wimbledon 2013
#2 Novak Djokovic vs Sam Querrey – Wimbledon 2016
#1 Rafael Nadal vs Robin Soderling – French Open 2009
